Medically Reviewed by Harshi Dhingra, M.D.

Last Reviewed: Jun 27, 2022

Side Effects


What are Norco (hydrocodone and acetaminophen) side effects?

The most common side effects of Norco are listed below. Contact your doctor if these side effects are severe or do not improve after a few days.

  • Drowsiness
  • Dizziness
  • Mood changes
  • Heartburn
  • Dry throat
  • Nausea
  • Vomiting
  • Constipation
  • Skin rash, itching
  • Difficulty urinating
  • Anxiety
  • Fuzzy thinking

Norco can cause certain serious side effects. Call your doctor right away if you experience:

  • Slow or irregular breathing
  • Chest tightness
  • Swelling of the throat, tongue, or face
  • Hallucinations, agitation, confusion
  • Nausea, vomiting, dizziness, weakness, high fever
  • Muscle stiffness
  • Irregular menstruation
  • Erection problems
  • Decreased sexual desire

The above list may not include all the potential adverse effects of Norco. Talk to your doctor if you have severe side effects or the side effects do not go away. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Norco Overdose: Call your doctor immediately in case of a known or suspected overdose. If the person can’t be awakened, has had a seizure, or has trouble breathing, call 911. Symptoms of Norco overdose may include narrowed or widened pupils; slowed, irregular, or stopped breathing; slowed, irregular, or stopped heartbeat; cold, clammy skin; excessive sleepiness or unresponsiveness; and seizures. 

While taking a product that contains hydrocodone, talk to your doctor about having a rescue medication called naloxone readily available in your home and office. Naloxone is used to reverse the life-threatening effects of an opioid overdose. You will need to make sure people in your household know how to recognize an overdose, how to use naloxone, and what to do until EMS arrives should an overdose occur.

NOTE: Norco is a prescription drug intended to be used only by the respective owners. Never share your prescription medication with others or use someone else’s Norco.

Source: FDA