Oxymetazoline

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: May 01, 2023

Common Questions


Common Questions about Oxymetazoline (Rhofade)


Is oxymetazoline over-the-counter?

No, oxymetazoline cream is only available with a doctor’s prescription.



Is oxymetazoline a steroid?

No, oxymetazoline is not a steroid. It is an alpha adrenergic receptor agonist and works by constricting blood vessels in the skin to reduce redness in the face caused by rosacea.



How long does oxymetazoline take to work for rosacea?

Oxymetazoline starts working right away. However, it can take several days to weeks to notice a significant difference in facial redness.



Is oxymetazoline cream safe for children?

Oxymetazoline cream is approved for use by adults 18 years of age and older. The safety and efficacy of this medicine in children have not been established. 



Can you use oxymetazoline every day?

You can use oxymetazoline cream every day to treat rosacea. However, you should not use oxymetazoline nasal spray for more than 3 days to treat nasal congestion.



What is the price of oxymetazoline without insurance?

Without insurance, oxymetazoline can be as high as $15.68, but with a free BuzzRx prescription discount coupon, you could pay as low as $4.81 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of oxymetazoline with insurance?

Ask your pharmacist or insurance provider for your copay price on oxymetazoline—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for oxymetazoline. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.