Lamotrigine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Aug 02, 2023

Pros & Cons


Lamotrigine Pros and Cons

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  • Lamotrigine comes in various dosage forms, including chewable tablets and orally disintegrating tablets, which makes it easy to take for people who have difficulty swallowing pills.
  • The extended release tablets only need to be taken once a day.
  • It is available in a lower-cost generic version.
  • Starter kits are available to make it easy to follow lamotrigine dosing instructions.
  • The dose can be adjusted based on clinical response.

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  • Lamotrigine can cause a potentially life-threatening severe skin rash.
  • It can lead to changes in mood and increase the risk of suicidal thoughts and behavior.
  • Lamotrigine can interact with other antiepileptic drugs. Taking it with certain anti-seizure medications can increase the risk of a severe skin reaction.
  • Lamotrigine can cause dizziness and drowsiness and increase the risk of falls and accidents.