Zestoretic

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Mar 20, 2023

Common Questions


Common Questions about Zestoretic


When is Zestoretic best taken?

Zestoretic is best taken once daily in the morning, with or without food. If the medicine makes you dizzy, it may help to take it before bedtime. However, remember that this medicine can make you urinate more, so take it at least 4 hours before bedtime. Try to take your medication at around the same time every day.



Does Zestoretic cause weight loss?

Zestoretic does not cause weight loss and it is not a weight loss drug. However, it contains hydrochlorothiazide, which is a diuretic or water pill that makes you urinate more and get rid of excess fluid. Therefore, Zestoretic may result in some weight loss if your body weight is due to fluid retention.



How quickly does Zestoretic start working?

Zestoretic starts working within a few hours of taking a dose. However, it can take 2-4 weeks to get the full benefit of this medicine. Check your blood pressure at home and tell your doctor if you do not notice a change in the readings after 4 weeks of taking lisinopril and hydrochlorothiazide.



Does Zestoretic cause impotence?

Impotence (erectile dysfunction) is not a known side effect of Zestoretic. In fact, this medicine can help in treating erectile dysfunction by treating high blood pressure.



What is the price of Zestoretic without insurance?

Without insurance, Zestoretic can be as high as $55.00, but with a free BuzzRx prescription discount coupon, you could pay as low as $7.73 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of Zestoretic with insurance?

Ask your pharmacist or insurance provider for your copay price on Zestoretic—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for Zestoretic. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.