Amoxicillin

Medically Reviewed by Harshi Dhingra, M.D.

Last Reviewed: Jun 16, 2022

Warnings


What are the risks of taking amoxicillin (Moxatag)?


Amoxicillin can cause serious health problems, especially in certain high-risk patients. If the potential complications of this medication concern you, talk to your doctor or pharmacist about other treatment options for bacterial infections. Potential risks of amoxicillin use include:

  • Severe allergic reaction: This risk is higher in people who have a history of penicillin allergy. Call your doctor immediately or go to the emergency room if you have symptoms such as difficulty breathing, severe rash, and/or swelling in any part of the body. 

  • Severe diarrhea: This can occur due to the amoxicillin killing the good bacteria necessary for a healthy gut. The risk of severe diarrhea with amoxicillin is higher in older individuals, in people taking amoxicillin for a long time, in those on immunosuppressant medications, and in those being treated with other antibiotics. Call your doctor immediately if you develop severe watery or bloody diarrhea. Note that these symptoms can occur several weeks after taking amoxicillin.

  • Rash: In people with a medical condition called mononucleosis (mono, Epstein-Barr virus, or kissing disease), amoxicillin can cause a widespread rash. Talk to your health care provider for other treatment options if you have mononucleosis.

Your doctor or pharmacist can prescribe other treatments for bacterial infections if you are at risk of complications from amoxicillin use.



What should I tell my doctor before starting amoxicillin (Moxatag)?

Tell your health care professional about all your medical conditions—amoxicillin may not be not suitable for people with certain medical conditions, such as mononucleosis, kidney disease, and others. If you have an inherited condition called phenylketonuria, know that amoxicillin chewable tablets contain aspartame as a sweetener, forming phenylalanine in the body.

Give your doctor a list of all your medications, including prescription drugs, over-the-counter medicines, dietary supplements, vitamins, and herbal products. This can help avoid serious drug interactions.

Tell your doctor if you have previously had an allergic reaction to penicillin antibiotics, cephalosporin antibiotics, or any of the ingredients in amoxicillin tablets, capsules, or liquid suspension. Ask your pharmacy for a list of ingredients.

Amoxicillin is a pregnancy category B drug. This means it is considered safe to take while pregnant and breastfeeding. However, you should tell your doctor if you’re pregnant, plan to become pregnant, or are breastfeeding. Also, tell your doctor if you become pregnant while on amoxicillin.

What precautions should I take while on amoxicillin (Moxatag)?

Keep all your doctors’ appointments while on treatment with amoxicillin. Your doctor may order some blood tests to assess your body’s response to the medicine.

Finish your prescription even if you feel better. Stopping amoxicillin without finishing the antibiotic course can lead to incomplete treatment of bacterial infections. It can also lead to the bacteria becoming resistant to antibiotics.

 Call your doctor immediately if you experience any signs and symptoms such as rash, hives, itching, difficulty breathing, swelling, or severe diarrhea while taking or after finishing amoxicillin.

People with diabetes should use TesTape or Clinistix (and not Clinitest) to test the urine for sugar while on amoxicillin.

Your amoxicillin prescription will likely not be refillable. If your symptoms have not improved after finishing amoxicillin, call your doctor. Do not use someone else’s leftover medicine or share your prescription with anyone.

What drugs can interact with amoxicillin (Moxatag)?

Taking amoxicillin with some other medications can affect how well the medicines work. Drug interactions can also increase the risk of serious side effects. Your physician may choose a different antibiotic to treat your bacterial infection, change the dose or frequency of one or both medicines, or monitor you carefully for side effects if there are known drug interactions. 

Caution is advised when using amoxicillin with the following medications:

  • blood thinners 
  • oral contraceptives
  • other antibiotics
  • allopurinol
  • probenecid

 This list does not describe all possible amoxicillin interactions. Give your health care provider a complete list of your medications, including prescription drugs, over-the-counter medicines, dietary supplements, vitamins, and herbal products. Also tell your health care provider if you smoke, drink alcohol, or use illegal drugs because some of these substances can cause serious health complications when used with antibiotics or other prescription drugs.